2011 Publications

Please visit each member in our FACULTY section for a more complete list of publications.



Aguilar-Valles A, Luheshi GN. Alterations in cognitive function and behavioral response to amphetamine induced by prenatal inflammation are dependent on the stage of pregnancy. Psychoneuroendocrinology. 2011 Jun;36(5):634-48

Alvarez JI, Cayrol R, Prat A. Disruption of central nervous system barriers in multiple sclerosis. Biochim Biophys Acta. 2011 Feb;1812(2):252-64.

Arnold D, Stone L. The clinical usefulness of routine MRI assessment. Int MS J. 2011 May;17(2):58-62.

Aubert-Broche B, Fonov V, Ghassemi R, Narayanan S, Arnold DL, Banwell B, Sled JG, Collins DL. Regional brain atrophy in children with multiple sclerosis. Neuroimage. 2011 Sep 15;58(2):409-15.



Bahcheli D, Hay V, Nadeau JL, Piccirillo CA. Transfer of cell membrane components via trogocytosis occurs in CD4(+)Foxp3(+)CD25(+) regulatory T-cell contact-dependent suppression. Autoimmunity. 2011 May 23.

Banner H, Bhat V, Etchamendy N, Joober R, Bohbot VD. The brain-derived neurotrophic factor Val66Met polymorphism is associated with reduced functional magnetic resonance imaging activity in the hippocampus and increased use of caudate nucleus-dependent strategies in a human virtual navigation task. Eur J Neurosci. 2011 Mar;33(5):968-77.

Banwell B, Bar-Or A, Arnold DL, Sadovnick D, Narayanan S, McGowan M, O’Mahony J, Magalhaes S, Hanwell H, Vieth R, Tellier R, Vincent T, Disanto G, Ebers G, Wambera K, Connolly MB, Yager J, Mah JK, Booth F, Sebire G, Callen D, Meaney B, Dilenge ME, Lortie A, Pohl D, Doja A, Venketaswaran S, Levin S, Macdonald EA, Meek D, Wood E, Lowry N, Buckley D, Yim C, Awuku M, Cooper P, Grand’maison F, Baird JB, Bhan V, Marrie RA. Clinical, environmental, and genetic determinants of multiple sclerosis in children with acute demyelination: a prospective national cohort study. Lancet Neurol. 2011 May;10(5):436-45.

Barclay-Goddard R, Ripat J, Mayo NE. Developing a model of participation post-stroke: a mixed-methods approach. Qual Life Res. 2011 Jul 12.

Berretta F, St-Pierre J, Piccirillo CA, Stevenson MM. IL-2 contributes to maintaining a balance between CD4+Foxp3+ regulatory T cells and effector CD4+ T cells required for immune control of blood-stage malaria infection. J Immunol. 2011 Apr 15;186(8):4862-71.

Bodnar M, Harvey PO, Malla AK, Joober R, Lepage M. The parahippocampal gyrus as a neural marker of early remission in first-episode psychosis: a voxel-based morphometry study. Clin Schizophr Relat Psychoses. 2011 Jan;4(4):217-28.

Buchy L, Ad-Dab’bagh Y, Malla A, Lepage C, Bodnar M, Joober R, Sergerie K, Evans A, Lepage M. Cortical thickness is associated with poor insight in first-episode psychosis. J Psychiatr Res. 2011 Jun;45(6):781-7.



Cayrol R, Haqqani AS, Ifergan I, Dodelet-Devillers A, Prat A. Isolation of human brain endothelial cells and characterization of lipid raft-associated proteins by mass spectroscopy. Methods Mol Biol. 2011;686:275-95.

Cencic R, Desforges M, Hall DR, Kozakov D, Du Y, Min J, Dingledine R, Fu H, Vajda S, Talbot PJ, Pelletier J. Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication. J Virol. 2011 Jul;85(13):6381-9.

Cinamon JS, Finch L, Miller S, Higgins J, Mayo N. Preliminary evidence for the development of a stroke specific geriatric depression scale. Int J Geriatr Psychiatry. 2011 Feb;26(2):188-98. doi: 10.1002/gps.2513

Comi G, Cohen JA, Arnold DL, Wynn D, Filippi M; FORTE Study Group. Phase III dose-comparison study of glatiramer acetate for multiple sclerosis. Ann Neurol. 2011 Jan;69(1):75-82. doi: 10.1002/ana.22316.

Cui K, Luheshi GN, Boksa P. Effects of endogenous glucocorticoid secretion on the interleukin-6 response to bacterial endotoxin in pregnant and non-pregnant rats. J Endocrinol. 2011 Apr;209(1):95-103



David S, Kroner A. Repertoire of microglial and macrophage responses after spinal cord injury. Nat Rev Neurosci. 2011 Jun 15;12(7):388-99

Demers M, Rouleau I, Scherzer P, Ouellet J, Jobin C, Duquette P. Impact of the Cognitive Status on the Memory Complaints in MS Patients. Can J Neurol Sci. 2011 Sep;38(5):728-33.

De Vidi I, Boursier G, Delouche N, Portalès P, Cadars E, Bouthier M, Mettling C, Lin YL, Thouvenot E, Carlander B, Camu W, Antel JP, Bar-Or A, Zephir H, Vermersch P, De Seze J, Corbeau P, Eliaou JF, Vincent T. Strategy for anti-aquaporin-4 auto-antibody identification and quantification using a new cell-based assay. Clin Immunol. 2011 Mar;138(3):239-46. Epub 2010 Dec 28.

d’Hennezel E, Piccirillo CA. Analysis of human FOXP3+ Treg cells phenotype and function. Methods Mol Biol. 2011;707:199-218.

d’Hennezel E, Yurchenko E, Sgouroudis E, Hay V, Piccirillo CA. Single-cell analysis of the human T regulatory population uncovers functional heterogeneity and instability within FOXP3+ cells. J Immunol. 2011 Jun 15;186(12):6788-97.

Dieudé M, Striegl H, Tyznik AJ, Wang J, Behar SM, Piccirillo CA, Levine JS, Zajonc DM, Rauch J. Cardiolipin binds to CD1d and stimulates CD1d-restricted γδ T cells in the normal murine repertoire. J Immunol. 2011 Apr 15;186(8):4771-81.

Disanto G, Magalhaes S, Handel AE, Morrison KM, Sadovnick AD, Ebers GC, Banwell B, Bar-Or A; Canadian Pediatric Demyelinating Disease Network. HLA-DRB1 confers increased risk of pediatric-onset MS in children with acquired demyelination. Neurology. 2011 Mar 1;76(9):781-6.

Doucet JD, Forget MA, Grange C, Rouxel RN, Arbour N, von Messling V, Lapointe R. Endogenously expressed matrix protein M1 and nucleoprotein of influenza A are efficiently presented by class I and class II major histocompatibility complexes. J Gen Virol. 2011 May;92(Pt 5):1162-71.

Durafourt BA, Lambert C, Johnson TA, Blain M, Bar-Or A, Antel JP. Differential responses of human microglia and blood-derived myeloid cells to FTY720. J Neuroimmunol. 2011 Jan;230(1-2):10-6.



Echeverry S, Shi XQ, Rivest S, Zhang J. Peripheral Nerve Injury Alters Blood-Spinal Cord Barrier Functional and Molecular Integrity through a Selective Inflammatory Pathway. J Neurosci. 2011 Jul 27;31(30):10819-28.



Filippi M, Rocca MA, Camesasca F, Cook S, O’Connor P, Arnason BG, Kappos L, Goodin D, Jeffery D, Hartung HP, Comi G, Wolinsky JS, Bogumil T, Pohl C, Beckmann K, Sandbrink R, Croze E, Brown C, Desimone TM, Arnold DL, Cutter G, Knappertz V. Interferon β-1b and glatiramer acetate effects on permanent black hole evolution. Neurology. 2011 Apr 5;76(14):1222-8.

Fisher RJ, Gaynor C, Kerr M, Langhorne P, Anderson C, Bautz-Holter E, Indredavik B, Mayo NE, Power M, Rodgers H, Rønning OM, Widén Holmqvist L, Wolfe CD, Walker MF. A consensus on stroke: early supported discharge. Stroke. 2011 May;42(5):1392-7.



Galanakis C, Mayo NE, Gagnon B. Assessing the role of hydration in delirium at the end of life. Curr Opin Support Palliat Care. 2011 Jun;5(2):169-73.

Garcia-Lorenzo D, Prima S, Arnold DL, Collins DL, Barillot C. Trimmed-likelihood estimation for focal lesions and tissue segmentation in multisequence MRI for multiple sclerosis. IEEE Trans Med Imaging. 2011 Aug;30(8):1455-67.

Giacomini PS, Bar-Or A. Laquinimod in multiple sclerosis. Clin Immunol. 2011 Mar 4.

Grange C, Létourneau J, Forget MA, Godin-Ethier J, Martin J, Liberman M, Latour M, Widmer H, Lattouf JB, Piccirillo CA, Cailhier JF, Lapointe R. Phenotypic characterization and functional analysis of human tumor immune infiltration after mechanical and enzymatic disaggregation. J Immunol Methods. 2011 Jul 18.

Greenwood J, Heasman SJ, Alvarez JI, Prat A, Lyck R, Engelhardt B. Review: leucocyte-endothelial cell crosstalk at the blood-brain barrier: a prerequisite for successful immune cell entry to the brain. Neuropathol Appl Neurobiol. 2011 Feb;37(1):24-39. doi: 10.1111/j.1365-2990.2010.01140.x. Review.



Haegert DG, Hackenbroch JD, Duszczyszyn D, Fitz-Gerald L, Zastepa E, Mason H, Lapierre Y, Antel J, Bar-Or A. Reduced thymic output and peripheral naïve CD4 T-cell alterations in primary progressive multiple sclerosis (PPMS). J Neuroimmunol. 2011 Apr;233(1-2):233-9.

Higgins J, Finch LE, Kopec J, Mayo NE. Development and initial psychometric evaluation of the Stroke Arm Ladder – a measure of upper extremity function post stroke. Clin Rehabil. 2011 Aug;25(8):740-59.



Iyer SN, Loohuis H, Pawliuk N, Joober R, Malla AK. Concerns reported by family members of individuals with first-episode psychosis. Early Interv Psychiatry. 2011 May;5(2):163-7.



Jelescu IO, Leppert IR, Narayanan S, Araújo D, Arnold DL, Pike GB. Dual-temporal resolution dynamic contrast-enhanced MRI protocol for blood-brain barrier permeability measurement in enhancing multiple sclerosis lesions. J Magn Reson Imaging. 2011 Jun;33(6):1291-300. doi: 10.1002/jmri.22565.

Johnson TA, Evans BL, Durafourt BA, Blain M, Lapierre Y, Bar-Or A, Antel JP. Reduction of the peripheral blood CD56(bright) NK lymphocyte subset in FTY720-treated multiple sclerosis patients. J Immunol. 2011 Jul 1;187(1):570-9.



Kaufman GN, Massoud AH, Audusseau S, Banville-Langelier AA, Wang Y, Guay J, Garellek JA, Mourad W, Piccirillo CA, McCusker C, Mazer BD. Intravenous immunoglobulin attenuates airway hyperresponsiveness in a murine model of allergic asthma. Clin Exp Allergy. 2011 May;41(5):718-28.

Kimball S, Vieth R, Dosch HM, Bar-Or A, Cheung R, Gagne D, O’Connor P, D’Souza C, Ursell M, Burton JM. Cholecalciferol Plus Calcium Suppresses Abnormal PBMC Reactivity in Patients with Multiple Sclerosis. J Clin Endocrinol Metab. 2011 Jun 22.

Kim HJ, Miron VE, Dukala D, Proia RL, Ludwin SK, Traka M, Antel JP, Soliven B. Neurobiological effects of sphingosine 1-phosphate receptor modulation in the cuprizone model. FASEB J. 2011 May;25(5):1509-18. Epub 2011 Jan 19.

Konsztowicz S, Xie H, Higgins J, Mayo N, Koski L. Development of a method for quantifying cognitive ability in the elderly through adaptive test administration. Int Psychogeriatr. 2011 Sep;23(7):1116-23.

Kornete M, Piccirillo CA. Critical co-stimulatory pathways in the stability of Foxp3(+) T(reg) cell homeostasis in Type I Diabetes. Autoimmun Rev. 2011 Aug 22

Krause D, Suh HS, Tarassishin L, Cui QL, Durafourt BA, Choi N, Bauman A, Cosenza-Nashat M, Antel JP, Zhao ML, Lee SC. The tryptophan metabolite 3-hydroxyanthranilic Acid plays anti-inflammatory and neuroprotective roles during inflammation role of hemeoxygenase-1. Am J Pathol. 2011 Sep;179(3):1360-72.



Larochelle C, Alvarez JI, Prat A. How do immune cells overcome the blood-brain barrier in multiple sclerosis? FEBS Lett. 2011 May 4.

Luck D, Buchy L, Czechowska Y, Bodnar M, Pike GB, Campbell JS, Achim A, Malla A, Joober R, Lepage M. Fronto-temporal disconnectivity and clinical short-term outcome in first episode psychosis: a DTI-tractography study. J Psychiatr Res. 2011 Mar;45(3):369-77.



Malla AK, Bodnar M, Joober R, Lepage M. Duration of untreated psychosis is associated with orbital-frontal grey matter volume reductions in first episode psychosis. Schizophr Res. 2011 Jan;125(1):13-20.

Mars LT, Saikali P, Liblau RS, Arbour N. Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models. Biochim Biophys Acta. 2011 Feb;1812(2):151-61. Epub 2010 Jul 15.

Mayo NE, Moriello C, Asano M, van der Spuy S, Finch L. The extent to which common health-related quality of life indices capture constructs beyond symptoms and function. Qual Life Res. 2011 Jun;20(5):621-7.

Miron VE, Kuhlmann T, Antel JP. Cells of the oligodendroglial lineage, myelination, and remyelination. Biochim Biophys Acta. 2011 Feb;1812(2):184-93.

Moriello C, Finch L, Mayo NE. Relationship between muscle strength and functional walking capacity among people with stroke. J Rehabil Res Dev. 2011;48(3):267-75.



Nadeau S, Filali M, Zhang J, Kerr BJ, Rivest S, Soulet D, Iwakura Y, de Rivero Vaccari JP, Keane RW, Lacroix S. Functional Recovery after Peripheral Nerve Injury is Dependent on the Pro-Inflammatory Cytokines IL-1{beta} and TNF: Implications for Neuropathic Pain. J Neurosci. 2011 Aug 31;31(35):12533-12542.

Nakashima I, Takahashi T, Cree BA, Kim HJ, Suzuki C, Genain CP, Vincent T, Fujihara K, Itoyama Y, Bar-Or A. Transient increases in anti-aquaporin-4 antibody titers following rituximab treatment in neuromyelitis optica, in association with elevated serum BAFF levels. J Clin Neurosci. 2011 Jul;18(7):997-8.

Nyirenda MH, Sanvito L, Darlington PJ, O’Brien K, Zhang GX, Constantinescu CS, Bar-Or A, Gran B. TLR2 Stimulation Drives Human Naive and Effector Regulatory T Cells into a Th17-Like Phenotype with Reduced Suppressive Function. J Immunol. 2011 Sep 1;187(5):2278-90.



Pittet CL, Newcombe J, Antel JP, Arbour N. The majority of infiltrating CD8 T lymphocytes in multiple sclerosis lesions is insensitive to enhanced PD-L1 levels on CNS cells. Glia. 2011 May;59(5):841-56. doi: 10.1002/glia.21158.

Pool M, Rambaldi I, Durafourt BA, Wright MC, Antel JP, Bar-Or A, Fournier AE. Myeloid lineage cells inhibit neurite outgrowth through a myosin II-dependent mechanism. J Neuroimmunol. 2011 Aug 15;237(1-2):101-5.

Prat A. Special issue on molecular basis of multiple sclerosis. Biochim Biophys Acta. 2011 Feb;1812(2):131. PubMed PMID: 21168062.

Pröbstel AK, Dornmair K, Bittner R, Sperl P, Jenne D, Magalhaes S, Villalobos A, Breithaupt C, Weissert R, Jacob U, Krumbholz M, Kuempfel T, Blaschek A, Stark W, Gärtner J, Pohl D, Rostasy K, Weber F, Forne I, Khademi M, Olsson T, Brilot F, Tantsis E, Dale RC, Wekerle H, Hohlfeld R, Banwell B, Bar-Or A, Meinl E, Derfuss T. Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis. Neurology. 2011 Aug 9;77(6):580-8.

Pruessner M, Iyer SN, Faridi K, Joober R, Malla AK. Stress and protective factors in individuals at ultra-high risk for psychosis, first episode psychosis and healthy controls. Schizophr Res. 2011 Jun;129(1):29-35.

Puts MT, Monette J, Girre V, Pepe C, Monette M, Assouline S, Panasci L, Basik M, Miller WH Jr, Batist G, Wolfson C, Bergman H. Are frailty markers useful for predicting treatment toxicity and mortality in older newly diagnosed cancer patients? Results from a prospective pilot study. Crit Rev Oncol Hematol. 2011 May;78(2):138-49.



Redensek A, Rathore KI, Berard JL, López-Vales R, Swayne LA, Bennett SA, Mohri I, Taniike M, Urade Y, David S. Expression and detrimental role of hematopoietic prostaglandin D synthase in spinal cord contusion injury. Glia. 2011 Apr;59(4):603-14.



Schirmer L, Antel JP, Brück W, Stadelmann C. Axonal loss and neurofilament phosphorylation changes accompany lesion development and clinical progression in multiple sclerosis. Brain Pathol. 2011 Jul;21(4):428-40. doi: 10.1111/j.1750-3639.2010.00466.x. Epub 2011 Jan 10.

Schneider R, Yaneva T, Beauseigle D, El-Khoury L, Arbour N. IL-27 increases the proliferation and effector functions of human naïve CD8+ T lymphocytes and promotes their development into Tc1 cells. Eur J Immunol. 2011 Jan;41(1):47-59.

Sgouroudis E, Kornete M, Piccirillo CA. IL-2 production by dendritic cells promotes Foxp3(+) regulatory T-cell expansion in autoimmune-resistant NOD congenic mice. Autoimmunity. 2011 Aug;44(5):406-14.

Shah M, Xiao Y, Subbanna N, Francis S, Arnold DL, Collins DL, Arbel T. Evaluating intensity normalization on MRIs of human brain with multiple sclerosis. Med Image Anal. 2011 Apr;15(2):267-82.

Shi XQ, Lim TK, Lee S, Zhao YQ, Zhang J. Statins alleviate experimental nerve injury-induced neuropathic pain. Pain. 2011 May;152(5):1033-43.

Shi XQ, Zekki H, Zhang J. The role of TLR2 in nerve injury-induced neuropathic pain is essentially mediated through macrophages in peripheral inflammatory response. Glia. 2011 Feb;59(2):231-41.

Soicher JE, Mayo NE, Gauvin L, Hanley JA, Bourbeau J. Trajectories of Endurance Activity following Pulmonary Rehabilitation in COPD Patients. Eur Respir J. 2011 Jul 7.

Steiger H, Fichter M, Bruce KR, Joober R, Badawi G, Richardson J, Groleau P, Ramos C, Israel M, Bondy B, Quadflieg N, Bachetzky N. Molecular-genetic correlates of self-harming behaviors in eating-disordered women: findings from a combined Canadian-German sample. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Jan 15;35(1):102-6.

Steiger H, Bruce K, Gauvin L, Groleau P, Joober R, Israel M, Richardson J, Kin FN. Contributions of the glucocorticoid receptor polymorphism (Bcl1) and childhood abuse to risk of bulimia nervosa. Psychiatry Res. 2011 May 15;187(1-2):193-7.



Tessier A, Mayo NE, Cieza A. Content identification of the IWQOL-Lite with the International Classification of Functioning, Disability and Health. Qual Life Res. 2011 May;20(4):467-77.

Till C, Ghassemi R, Aubert-Broche B, Kerbrat A, Collins DL, Marayana S Arnold DL, Desrocher M, Sled JG, Banwell. MRI correlate of cognitive impairment in childhood-onset multiple sclerosos. Neuropsychology. 2011 May; 25(3):319-32



Venkateswaran S, Zheng K, Sacchetti M, Gagne D, Arnold DL, Sadovnick AD, Scherer SW, Banwell B, Bar-Or A, Simon DK; Canadian Pediatric Demyelinating Disease Network. Mitochondrial DNA haplogroups and mutations in children with acquired central demyelination. Neurology. 2011 Mar 1;76(9):774-80.



Xie H, Mayo N, Koski L. Identifying and characterizing trajectories of cognitive change in older persons with mild cognitive impairment. Dement Geriatr Cogn Disord. 2011;31(2):165-72.



Yao H, Kim K, Duan M, Hayashi T, Guo M, Morgello S, Prat A, Wang J, Su TP, Buch S. Cocaine hijacks σ1 receptor to initiate induction of activated leukocyte cell adhesion molecule: implication for increased monocyte adhesion and migration in the CNS. J Neurosci. 2011 Apr 20;31(16):5942-55.