// This is the Database of Upcoming Events
// Please Edit with Care.
//


member = new Array(
["Antel, JP", "Antel", "Jack", "MD","Professor","McGill University, Montreal Neurological Institute", "3801 University Street, room 111, Montreal, QC H3A 2B4", "514-398-3413", "(514) 398-7371","jack.antel@mcgill.ca", "http://www.mni.mcgill.ca/neuro_team/cru/jack_antel/", "The research program focuses on using human neural and immune cells to understand how their interactions can contribute to development of neurologic disease, specifically multiple sclerosis. The studies include how immune cells reach the central nervous system, how the state of activity of the endogenous glial cells contributes to persistence of the immune response, and how the immune mediators actually induce injury of the target cells, names oligodendrocytes and neurons and their processes. The corollary of these studies is to understand how the nervous system is able to repair itself from such injury." , "Interests include interactions between the immune and central nervous systems and inflammatory demyelinating disorders, including multiple sclerosis."],	
["", "Arbour", "Nathalie", "PhD","Research assistant professor","Department of medicine, Université of Montréal, Centre de recherche du CHUM-Hôpital Notre-Dame", "Pavillon JA De Sève (Y3609), 1560 Sherbrooke Est Montréal, Qc, Canada, H2L 4M1", "(514) 890-8000 (25112)", "(514) 412-7602","nathalie.arbour@umontreal.ca", '','Human and animal neuroimmunology (mouse models), auto-immunity, multiple sclerosis, T and B lymphocytes, virology, central nervous system, cytokines, in vitro immunological studies, tissue cultures, flow cytometry, cell and molecular biology.', 'Neuroimmunology: interactions between two complex systems, the immune system and the central nervous system (brain and spinal cord). Identification of key players involved in the deleterious dialogue between the immune and the central nervous systems and thus implicated in the pathogenesis of demyelinating, neurodegenerative and virus-induced diseases. Elucidation of the mechanisms exploited by T lymphocytes (CD8 and CD4) to attack cells of the central nervous system and thus contributing to the patho¬¬genesis of autoimmune diseases such as multiple sclerosis. Characterisation of molecules (ligands, cytokines, intracellular proteins) expressed by the central nervous system to locally modulate immune responses.'],
["", "Arnold", "Douglas", "MD","Professor","McGill University, Montreal Neurological Institute", "3801 University Street, Montreal, QC H3A 2B4", "514-398-8185", "514-398-2957","doug@mrs.mni.mcgill.ca", "http://www.mni.mcgill.ca/neuro_team/mbic/douglas_arnold/", "Advanced MRI acquisition and analysis methods for evaluation of multiple sclerosis (MS) and other neurological disorders." , "MRI, MRS, Multiple Sclerosis, Neurological disorders"],
["", "Bar-Or", "Amit", "MD, FRCP(C)","Associate Professor","McGill University, Montreal Neurological Institute", "3801 University Street, Montreal, QC H3A 2B4", "514-398-5950", "514-398-7371","amit.bar-or@mcgill.ca", "http://www.mni.mcgill.ca/neuro_team/cru/amit_bar_or/", "Dr. Amit Bar-Or directs a cellular and molecular immunology lab studying mechanisms of autoimmune disease with a focus on multiple sclerosis (MS). His research is directed at understanding basic principles of immune regulation and immune-neural interactions." , "Of particular interest are studies of B cell, antigen presenting cell, and T cell responses and their involvement in central nervous system inflammation. Studies of the immature immune system in the context of early onset (pediatric) MS, and reconstitution following immune ablation, are also being pursued, as are studies of immuneneural interaction. Dr. Bar-Or has established a program in ‘Experimental Therapeutics’, which aims to develop and incorporate novel immune assays into well-designed clinical trials of MS. This approach provides a unique opportunity to gain insights into disease mechanisms and to develop biomarkers of response to therapy while also evaluating the safety and efficacy of novel therapies in clinically well-characterized patients with MS. "],
["", "David", "Samuel", "PhD","Professor","Center for Research in Neuroscience, MUHC", "1650 Cedar Ave., Montreal, H3G 1A4", "514-934-1934 (44240)", "514-934-8216","sam.david@mcgill.ca", "http://www.mcgill.ca/crn/investigators/david/", "My laboratory is interested in three areas: (1) Autoimmune demyelinating disease (Multiple sclerosis). We are studying the role of cytosolic phospholipase A2 (cPLA2) in mouse models of MS called experimental autoimmune encephalitis (EAE). Our work has led to the discovery of a novel therapeutic target for the treatment of the relapsingremittingform EAE. The current work is focused on the differences between relapsing-remitting and chronic EAE and the cellular mechanisms underlying the effects of cPLA2. (2) CNS Regeneration. We are studying ways in which antibody and immune cell mediated responses can be recruited to promote axon regeneration in the adult mammalian CNS. The work on the antibody responses is directed at the development and use of a therapeutic vaccine to block axon growth inhibitors associated with myelin in spinal cord injury. We are also characterizing the molecular and functional phenotype of macrophage activation in the CNS. (3) Neurodegenerative disease. We are currently studying the role of ceruloplasmin, iron transporters and binding proteins in maintaining iron homeostasis in the CNS. We are also studying the involvement of these iron homeostasis proteins in spinal cord injury and neurodegenerative diseases such as ALS. " , "Cell biology, molecular and biochemical techniques, in vivo models, cell culture, anatomical and histological techniques."],
["", "Duquette", "Pierre", "MD","Professor","Hôpital Notre-Dame - CHUM", "1560 Sherbrooke Street East - H-3135 Montréal, QC H2L 4M1", "(514) 890-8212", "(514) 412-7668","pierre.duquette.chum@ssss.gouv.qc.ca ", "http://www.cenum.umontreal.ca/membres/2_titulaires/en_duquette_p.html", "Involved in studies on several aspects of multiple sclerosis: clinical, epidemiology, genetics, immunology, clinical trials." , "Multiple Sclerosis, Amyotrophic lateral sclerosis"],
["", "Fournier", "Sylvie", "PhD","Associate Professor","McGill University, Department of Microbiology and Immunology", "3775 University Street, room 616, Montreal, QC H3A 2B4", "(514) 398-7273", "(514) 398-7052","sylvie.fournier@mcgill.ca",'http://www.mcgill.ca/microimm/department/professors/fournier/', 'Our research program focuses on assessing in vivo the consequences of dysregulated expression of tne costimulatory ligand B7.2 (CD86) on T lymphocyte responses and development.  We have generated transgenic mouse lines in which various physiologically relevant cell types constitutively express this molecule. We showed that transgenic mice constitutively expressing B7.2 on microglia, a nervous tissue resident antigen presenting cells, spontaneously develop a CD8+ T-cell mediated demyelinating disease.  A large part of our current research activities is focused on defining the pathogenic mechanisms involved in this novel animal model of CD8+ T cell-mediated demyelinating disease and the antigenic specificity of the CNS CD8+ T cells that are activated by B7.2-expressing microglial cells.', 'Immunology, Costimulation, B7/CD28/CTLA-4, T lymphocytes, Autoimmunity, Neuroimmunology, Transgenic and knock-out/in mouse models, Flow cytometry, Cell and molecular biology.'],
["", "Joober", "Ridha", "MD PhD","Associate Professor","Douglas Hospital Research Centre, McGill University", "6875, LaSalle Boulevard, Verdun, Quebec, H4H 1R3", "(514) 761 6131 (2404)", "(514) 888 4064","ridha.joober@douglas.mcgill.ca", "http://www.douglasrecherche.qc.ca/profiles/details.asp?l=e&id=77", "Afflicting one percent of the adult population with devastating hallucinations, delusions and social impairment, schizophrenia has long been known to have a genetic component. Ridha Joober, MD, PhD, joined the Douglas Hospital Research Centre in 1999 and has since made significant strides in unveiling the pharmaco-genetic basis of schizophrenia and in identifying genes modulating animal behavioral traits relevant to schizophrenia. He is also co-director of the Research Centre’s Schizophrenia and Neurodevelopmental Disorders Research Theme. Affiliated with McGill University, Ridha Joober currently holds positions as assistant professor with the Department of Psychiatry, and associate member with the departments of genetics and neurology & neurosurgery." , "Genetics, schizophrenia, autism, ADHD, animal models, QTL mapping"],
["", "Luheshi", "Giamal N.", "PhD","Professor","Douglas Hospital Research Centre, McGill University", "6875, LaSalle Boulevard, Verdun, Quebec, H4H 1R3", "(514) 761 6131 (4927)", "(514) 762 3034","Giamal.luheshi@mcgill.ca", "http://www.douglasrecherche.qc.ca/profiles/details.asp?id=80&l=e", "Investigating interactions between the immune system and the brain. In particular, we are interested in how the immunemediators ‘cytokines’ influence brain regulation of sickness behaviors such as fever and appetite control following systemic infection, inflammation or injury. More recently we have initiated a research program to investigate the link between maternal infection during pregnancy with the development and progression of mental disorders such as Schizophrenia, in the adult offspring. This work is primarily focussed on the role of cytokines in fetal brain development. These investigations utilize an array of integrated approaches involving well-established in vivo and in vitro techniques." , "Neuroimmune interactions, infection, inflammation, fever, appetite control"],
["", "Mayo", "Nancy E.", "PhD","James McGill Professor","Department of Medicine, School of Physical and Occupational Therapy", "Royal Victoria Hospital Ross Pavilion R4.29687, Pine Ave West, Montreal, QC, H3A 1A1", "(514) 842 1231 (36922)", "(514) 843 1493","nancy.mayo@mcgill.ca", "http://www.mcgill.ca/cihr-pcresearch/investigators/mayo/", "Nancy Mayo has two major research programs: one on stroke and one related to health services and outcomes research. The unifying theme of her research is outcome measurement and improvement and use of administrative databases for clinical research. In the arena of health services and outcomes research, she has applied knowledge of modeling time to discharge to waiting time for breast cancer surgery and examined variation in waiting time and also in stroke hospitalization outcomes. She has conducted a number of clinical trials on service delivery for persons with stroke and has just completed a large database study with Dr Bruno Gagnon on end-of-life care for women dying of breast cancer. In the area of stroke, she has investigated the impact of stroke on the individual, the family and society. This led her to do research in the area of outcomes: impairments, disability, handicap, and QOL, as well as on the impact on caregivers and society at large, in terms of population burden. This research program pointed out gaps in the care that stroke patients receive and led to a series of clinical trials evaluating care-delivery models (home-based rehabilitation, case-management to enhance continuity of care, late rehabilitation), cost-effectiveness and policy implications." , ""],

["", "Nalbantoglu", "Josephine", "PhD","Associate Professor","McGill University, Montreal Neurological Institute", "3801 University Street, Montreal, QC H3A 2B4", "514-398-5920", "514-398-7371","josephine@microimm.mcgill.ca", "http://www.mcgill.ca/translational-research-cancer/researcher-biographies/nalbantoglu/", "There are three broad areas of research in the lab – gene therapy of brain tumours, gene therapy of muscle diseases and functional studies on CAR (coxsackie and adenovirus receptor). We use adenovirus and adeno-associated virus vectors for suicide gene therapy and anti-angiogenic therapy in xenograft models of brain tumours. We are optimizing vascular delivery of viral vectors to disseminated tumours as well as developing gene transfer methods to target cancer stem cells. The study of the physiological function of CAR is a major focus of the laboratory. We have shown CAR to be a suppressor of tumour growth and invasion for gliomas. We are identifying the proteins and pathways which mediate this effect of CAR. As the highest expression of CAR is in the developing nervous system, we are using a variety of approaches to study the role of CAR neuronal function (primary cultures, conditional knockouts, behavioral analysis)." , "Adenovirus-mediated gene therapy of experimental gliomas and medullablastomas using tumour suppressor and 'suicide' genes"],


["", "Piccirillo", "Ciriaco", "PhD","Assistant Professor and Canada Research Chair","Department of Microbiology and Immunology, McGill University and Center for the Study of Host Resistance, MUHC", "3775 University Street, Room 510, Montreal, QC H3A 2B4", "(514) 398-2872", "(514) 398-7052 ","ciro.piccirillo@mcgill.ca", 'http://www.mcgill.ca/microimm/department/professors/piccirillo/', 'The research program focuses on the regulation of immune responses mediated by CD4+Foxp3+ Treg, a unique population of cells with potent immunosuppressive and tolerogenic functions in mice and humans. Our laboratory aims to characterize the relative contribution of CD4+ Treg cells as a determining factor in establishing resistance or susceptibility to autoimmune and infectious diseases, as well as controlling immunity to tumors. Our group makes use of cutting-edge experimental strategies to characterize the functional dynamics of CD4+Foxp3+ Treg cell activity in human autoimmune diseases (type 1 diabetes, MS, IBD) as well as in animal models of autoimmunity (type 1 diabetes, EAE), tumours (breast cancer), infections (malaria), and mucosal immunity (IBD). Our research program also focuses on the development of novel immunotherapeutic strategies to manipulate CD4+Foxp3+ Treg cell function and ultimately modulate autoimmune and chronic inflammatory diseases. Our research program makes use of standard and state-of-the-art molecular, cellular and imaging approaches in a variety of gene-modified mouse models (knock-out, transgenic and knock-in) and in human subjects to monitor and characterize the functional dynamics of nTreg cells in health and disease.','Cellular and molecular immuno-biology, in vitro immunological studies, human and mouse models of disease, T cells, dendritic cells, cytokines, multi-parametric flow cytometry.'],
["", "Prat", "Alexandre", "MD, PhD","Assistant Professor","Université de Montréal", "Hôpital Notre-Dame - CHUM", "1560 Sherbrooke Street East, Montréal, QC H2L 4M1", "(514) 890-8000 (24734)", "(514)412-7668","a.prat@ umontreal.ca", "", "Immunobiology, cell biology and pharmacology of the human Blood brain barrier. Immunobiology of the BBB in multiple sclerosis. Astrocytes – brain microvascular endothelium interactions in the human brain. Molecular phenotyping of BBB tight junction in the human brain. Regulation of TJ formation in the human brain(supported by the MSSC). Characterization of dendritic cell population within the human brain. Identification of the molecular signals provided by BBB endothelium to promote the differentiation, maturation and migration of DC within the human brain. Identification of the clinical, radiological and immuno-biological pronostic factors involved in the conversion of the clinically isolated syndromes into clinically definite multiple sclerosis. (supported by the FRSQ)" ,"Human Immunology and Autoimmunity, Human Blood-Brain Barrier Physiology, Cell biology and Pharmacology, Drug delivery through the BBB, Human astrocytes, Tight junction proteins, Retroviral delivery, siRNA, Immune cell migration, Chemokines, cytokines and adhesion molecules"],
["", "Talbot", "Pierre", "PhD","Professor","INRS-Institut Armand-Frappier, Université du Québec", "531, boulevard des Prairie, Laval, QC H7V 1B7", "(450) 686-5515", "(450) 686-5566","Pierre.Talbot@iaf.inrs.ca", "http://www.iaf.inrs.ca/Anglais/index.jsp?page=Home", "Dr. Talbot’s research program deals with coronaviruses in the context of neuroinflammatory and neurodegenerative diseases such as multiple sclerosis (MS), in patients, in neural cell cultures and in an animal model of virus-induced MS-like diseases. Multiple sclerosis disease etiology is not known but is suspected to involve both genetic susceptibility and environmental triggering factors, the latter most likely viruses. It is suspected that infection by one or several common pathogen(s) before adolescence triggers MS in genetically susceptible individuals, as manifested by autoimmune reactions against antigens of the myelin sheaths surrounding nerve fibers in the central nervous system (CNS), as well as neurodegeneration. Among the several viral candidates for induction of MS are the coronaviruses, a family of common respiratory pathogens involved in as many as 30% of common colds (a variant of which causes SARS) and which cause neurologic diseases in mice, as animal model of human disease. Importantly, strains of murine coronavirus (MHV) cause an acute encephalitis that develops into a chronic recurrent demyelinating disease that is one of the best animal model of human MS. Dr. Talbot's research team has detected the presence of these viruses in human brains, determined the susceptibility to human coronavirus infection of neural and glial cells in continuous and primary cultures, as well as their activation to produce neuroinflammatory mediators, and identified a striking human coronavirus-myelin cross-reactive T-cell response in MS patients but not controls, even at the clonal level. Moreover, he has recently shown that murine coronavirus infection of mice triggers both the activation of myelin-reactive T-cells and a transient immunosupppression, and that human respiratory coronaviruses cause an encephalitis in mice that is transformed to a demyelinating MS-like disease after evolution of virus in persistent infections of human neural cells. Studies in progress deal mostly with the characterization of the interaction of human coronaviruses with target human neurons ex vivo, and with the immune and nervous systems of susceptible mice that leads to neuropathogenesis in the animal model of neurologic diseases with a probable viral component, such as multiple sclerosis." , "Coronavirus, virus, neurotropism, neuroinvasion, multiple sclerosis, neurological disease, immunology, autoimmunity, animal models, neurons"],
["", "Wolfson", "Christina", "PhD","Professor","McGill University, Centre for Clinical Epidemiology and Community Studies", "3755 Côte St. Catherine, Suite A-114, Montreal, Quebec, H3T 1E2", "(514) 340-7563", "(514) 340-7594","christina.wolfson@mcgill.ca", 'http://www.medicine.mcgill.ca/epidemiology/wolfson/', 'Professor Christina Wolfson is Director of the Division of Clinical Epidemiology at the McGill University Health Centre and a Professor in the Department of Epidemiology and Biostatistics and Occupational Health and in the Department of Medicine at McGill University.  She is an Associate Member in the Department of Neurology and Neurosurgery, the Department of Mathematics and Statistics and the Division of Geriatric Medicine at McGill University. Her program of research lies in the epidemiology of neurodegenerative disorders, including dementia, multiple sclerosis, amyotrophic lateral sclerosis and Parkinson’s disease. She is also co-Principal Investigator on the Canadian Longitudinal Study on Aging, a nation wide 20-year study of 50,000 participants aged 45 to 85 to be launched in 2009.  Dr. Wolfson received her BSc in Mathematics and MSc in Mathematical Statistics from the Department of Mathematics and Statistics, and PhD in Epidemiology and Biostatistics from the Department of Epidemiology & Biostatistics at McGill University.', "Epidemiology, Population Health Research, Health Services Research, Biostatistics."],
["", "Zhang", "Ji", "MD PhD","Assistant Professor","The Alan Edwards Centre for Research on Pain, McGill University", "740 Dr. Penfield Avenue, Suite 3200C, Genome Building, Montreal, QC H3A 2B2", "(514) 398-7203 (00036)", "(514) 398-8121","Ji.Zhang@mcgill.ca", 'http://www.mcgill.ca/dentistry/research/zhang/', 'The overall goal of the research program is to investigate the immune factors that contribute to the etiology of chronic pain by exploring the interactions between injured neurons and their surrounding glial cells, and the impact of glial cell activation on pain behaviour. Current research projects include: 1) Identifying the origins of activated spinal microglia and investigating the distinct contribution of CNS-resident microglia and peripheral macrophages to the development of neuropathic pain, 2) Identifying the triggers that induce spinal microglial activation following peripheral nerve injury, 3) Examining glial cell activation in other neuropathic pain, particularly multiple sclerosis-related central neuropathic pain, and 4) Characterizing microglia phenotypes in response to different stimuli at different stages.  Understanding how glial cells dynamically influence neuronal signal transmission will advance mechanistic studies for chronic pain and open new avenues for effective treatment.', "In vivo animal models (inflammatory, neuropathic pain model, EAE model), anatomical techniques, molecular and biochemical methods, pain behavioral studies, gene/protein expression, immune response, cytokine/chemokine, glial cells."],







["","","",""]	

// Please omit the final comma after the ] from the last line above unless you are going to add another event at this time.
);